向攀,王芳,郜桂菊,韩宁,张伟,焦以庆,熊号峰,刘景院,赵红心

• 1:首都医科大学附属北京地坛医院

摘要(Abstract)：

目的探讨艾滋病(AIDS)合并巨细胞病毒脑炎(CMVE)的临床特点及治疗转归。方法回顾性地收集北京地坛医院2011年3月-2013年2月收治的8名合并CMVE的AIDS病人的临床资料,分析其症状和体征、辅助检查、病毒学检查及治疗转归情况。结果 8例病人脑脊液CMV脱氧核糖核酸(DNA)或CMV-IgM抗体阳性,但血清中CMV DNA可阴性。7例CD4+淋巴细胞计数均<30/μL,轻症、早期病人可不伴随神经精神症状,头颅核磁共振(MRI)检查可无异常,7例患者经抗CMV及高效抗反转录病毒治疗(HAART)后均获得临床好转。结论合并CMVE易出现在CD4+淋巴细胞计数低的AIDS病人中,及时对可疑病人进行脑脊液CMV DNA或CMV-IgM抗体检查,有利于早期诊断和治疗。

关键词(KeyWords)： 艾滋病;巨细胞病毒脑炎;临床分析

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 向攀,王芳,郜桂菊,韩宁,张伟,焦以庆,熊号峰,刘景院,赵红心

DOI: 10.13419/j.cnki.aids.2013.08.013

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